Conference: Hockey East | Roster | StatsHead Coach: Blaise MacDonald
Home Ice: Tsongas Arena, Lowell, MA
2009-2010 Record: 19-16-4
| Record | Score | Date | Time | Opponent | Arena | Other Info | |
| 0-1-0 | 2-8 | 10/08/10 | 7:00PM | at Maine | Alfond | ||
| 0-1-1 | 2-2 TIE | 10/15/10 | 7:05PM | at Niagara | Dwyer | ||
| 0-1-2 | 4-4 TIE | 10/16/10 | 7:05PM | at RIT | Ritter | ||
| 1-1-2 | 5-4 OT | 10/22/10 | 7:00PM | Providence | Tsongas | ||
| 1-2-2 | 1-3 | 10/23/10 | 7:00PM | Northeastern | Tsongas | ||
| 1-3-2 | 1-5 | 10/29/10 | 7:00PM | Boston U | Tsongas | ||
| 1-4-2 | 1-2 | 10/30/10 | 7:00PM | at Boston U | Agganis | ||
| 11/02/10 | 7:00PM | at Boston College | Conte | ||||
| 11/05/10 | 7:00PM | Vermont | Tsongas | ||||
| 11/06/10 | 7:00PM | New Hampshire | Tsongas | ||||
| 11/19/10 | 7:00PM | Merrimack | Tsongas | ||||
| 11/20/10 | 7:00PM | at Merrimack | Lawler | ||||
| 11/26/10 | 7:00PM | Minnesota State | Tsongas | ||||
| 11/27/10 | 4:00PM | Minnesota State | Tsongas | ||||
| 12/02/10 | 7:00PM | New Hampshire | Tsongas | ||||
| 12/04/10 | 1:30PM | at Massachusetts | Mullins | ||||
| 12/10/10 | 7:00PM | at Princeton | Baker | ||||
| 12/11/10 | 7:00PM | at Princeton | Baker | ||||
| 01/07/11 | 7:00PM | at New Hampshire | Whittemore | ||||
| 01/08/11 | 7:00PM | at Northeastern | Matthews | ||||
| 01/14/11 | 7:30PM | Massachusetts | Tsongas | ||||
| 01/15/11 | 7:00PM | at Massachusetts | Mullins | ||||
| 01/21/11 | 7:00PM | at Merrimack | Lawler | ||||
| 01/22/11 | 7:00PM | at Boston College | Conte | ||||
| 01/25/11 | 7:00PM | Bentley | Tsongas | ||||
| 01/29/11 | 7:00PM | Boston College | Tsongas | ||||
| 02/04/11 | 7:00PM | at Boston U | Agganis | ||||
| 02/11/11 | 7:00PM | Northeastern | Tsongas | ||||
| 02/18/11 | 7:00PM | Maine | Tsongas | ||||
| 02/19/11 | 7:30PM | Maine | Tsongas | ||||
| 02/25/11 | 7:00PM | at Providence | Schneider | ||||
| 02/26/11 | 7:00PM | Providence | Tsongas | ||||
| 03/04/11 | 7:05PM | at Vermont | Gutterson | ||||
| 03/05/11 | 7:05PM | at Vermont | Gutterson | ||||
| 03/11/11 | TBD | HE Playoffs QF | High Seed | ||||
| 03/17/11 | TBD | HE Playoffs SF | TD Garden | Boston, MA | |||
| 03/18/11 | TBD | HE Playoffs Final | TD Garden | Boston, MA | |||
| 03/25/11 | TBD | NCAA Regionals | TBD | ||||
| 04/07/11 | TBD | NCAA Frozen Four | Xcel Energy | St. Paul, MN |
